SKU: I041

    Epi-Ivermectin B1a

    ¥3,820.75 - ¥13,332.75

    Epi-Ivermectin B1a is a base-catalysed intermediate in the decomposition of Ivermectin. Epi-Ivermectin B1a is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analog, Δ 2 -ivermectin B1a. Despite the importance of Ivermectin as an anthelmintic in animal health, there are no published reports of the biological activity or the levels of Epi-Ivermectin B1a in animals or the environment.

    Epi-Ivermectin B1a is soluble in ethanol, methanol, DMF or DMSO.

    References Base-catalyzed isomerization of avermectins. Pivnichny J.V. et al. J. Agric. Food Chem. 1988, 36, 826.

    Direct determination of avermectins in plasma at nanogram levels by High-Performance Liquid Chromatography. Pivnichny J.V. et al. J. Pharm. Sci. 1980, 72, 1447.