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Himbosine

Himbosine is apiperidine alkaloid with a complex polycyclic scaffold first isolated from Galbulimima sp., a magnolia species native to Australia and South East Asia, and reported in 1967 by Taylor and co-workers, University of Sydney, Australia. The...

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Hecogenin Acetate

Hecogenin Acetate is a steroidal saponin first published in 1943 by Marker and colleagues at Penn State University and isolated from Agave.  Hecogenin Acetate induces cell cycle arrest and senescence, and modulates ERK1/2 phosphorylation and MMP-2...

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Hesperidin

Hesperidin is a flavonoid produced by citrus species, first published in 1943. Hesperidin has a broad pharmacological profile, including antihyperlipidemic, cardioprotective, antihypertensive and antidiabetic activities, mainly attributed to antioxidant...

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IT-143A

IT-143-A is a rare, higher homolog of the piericidin class isolated from a Streptomyces sp. by Taiho Pharmaceuticals incollaboration with Chinese researchers in 1996. IT-143-A is active against the fungus, Aspergillus fumigatus, and the Gram-positive...

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IT-143B

IT-143B is a rare, higher homolog of the piericidin class isolated from a Streptomyces sp. by Taiho Pharmaceuticals incollaboration with Chinese researchers in 1996. IT-143B is active against the fungus, Aspergillus fumigatus, and the Gram-positive...

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Janthitrem A

Janthitrem A is a fluorescent indole-diterpenoid tremorgenic mycotoxin produced by Penicillium janthinellum-infected rye grass discovered by Gallagher and colleagues at CSIR, New Zealand in 1980. Interestingly, the structure of jJanthitrem A was only...

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Karrikinolide

Karrikinolide (KAR1) was discovered by Ghisalberti, Flematti and colleagues, University of Western Australia in 2009.Karrikinolide, found in smoke water extracts, acts as a key germination trigger for many species from fire-prone, Mediterranean climates,...

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Karrikin 2

Karrikin 2, found in smoke water extracts, acts as a key germination trigger for many species from fire-prone Mediterranean climates, but is also active in plants from temperate regions. Karrikin 2 is more active than karrikinolide and KAR3 in promoting...

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Limonin

Limonin is a highly oxygenated terpenoid which forms the core structure of the citrus limonoid metabolites found mostly in the seeds, fruits and peel tissues of citrus. Limonin was first isolated over 175 years ago. In Australia, Limonin was isolated...

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Lupeol

Lupeol is a pentacyclic lupane triterpene produced by various fruits, vegetables and other plants, first isolated in 1898 and published in 1907. Lupeol is reported to have very diverse biological effects, including anti-inflammatory, anti-diabetic,...

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Lepimectin A4

Lepimectin A4 is a the major analog of a complex of semi-synthetic milbemycins synthesised from 15-hydroxy-5-ketomilbemycin A3/A4 by coupling to methoxyiminophenylacetic acid and then reducing with sodium borohydride.Commercially, Lepimectin is a mixture...

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Leoidin

Leoidin is a metabolite of the lichen, Lecanora gangleoides, first published in 1986 and recently reported as an inhibitor ofprotein synthesis in Pseudomonas aeruginosa. Leoidin is bacteriostatic, targeting PheRS. Leoidin is a weak inhibitor of human...

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