Bioactive small molecules are organic compounds that have a low molecular weight (900 daltons). Most pharmaceutical drugs are small molecules. Larger structures such as nucleic acids, proteins, and many polysaccharides are not small molecules.
Aminopterin is a 4-amino derivative of folic acid and a folic acid antagonist. It is a synthetic derivative of pterin. It has both mmunosuppressive properties and anti-cancer properties and can be used for apoptosis research. The compound was discovered...
Alternariol is a mycotoxin produced by Alternaria and is often found as a contaminant in fruit and small grain cereal products. Structurally, it is characterized as a dibenzopyranone. It can be used as an analytical standard. The...
Acetomycin, a γ-butyrolactone isolated from Streptomyces ramulosus, was first reported in 1958 by Ettlinger et al. at ETH Zurich. Acetomycin is potently active in vitro against HCT-8 human colon adenocarcinoma cells and L1210 murine leukemia cells...
Acadesine was originally identified as a metabolite of Bacillus species and was shown to accumulate in the culture medium of E. coli under sulphonamide stasis. Acadesine is an adenosine-regulating agent that increases bioavailability of adenosine. Ithas...
6-Diazo-5-oxo-L-norleucine (syn: DON) is a natural antibiotic and glutamine antagonist originally isolated from Streptomyces sp from a Peruvian soil sample in 1954. The compound has anti-cancer properties, disrupting the mitochondrial internal...
17-Dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG, alvespimycin) is a semi-synthetic derivative of the benzoquinone ansamycin antibiotic isolated from Streptomyces hygroscopicus in which the methoxy group attached to...
Sulfasalazine is a synthetic salicylic acid derivative and sulfonamide which can act as an antirhematic and gastrointestinal agent. It is formulated as a prodrug, and is metabolized into active metabolites sulfapyridine and mesalazine (5-aminosalicylic...
Baloxavir Marboxil is a synthetic antiviral compound. It has activity against viruses causing influenza A and influenza B. It originated by Shionogi (Japan). It is a small molecule inhibitor of cap-dependent endonuclease found in of influenza A and B...
Sulfachloropyridazine Sodium is the sodium salt of Sulfachloropyridazine, a sulfonamide antibiotic. It has been used to treat the bacteria causing urinary tract infections and is commonly used in aquaculture and animal husbandry. Sulfachloropyridazine...
Pretomanid is a bicyclic nitroimidazole and small molecule pro-drug that is active against actively replicating and hypoxic non-replicating Mycobacterium tuberculosis, the causative agent of tuberculosis (TB). It is activated by deazaflavin-dependent...
Podophyllotoxin, a natural, non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species, was first isolated in 1880. Serving as a model for antii-tumor properties, Podophyllotoxin has been used to inhibit the growth of various...
4-Epitetracycline ammonium salt, EvoPure® is a highly purified version of 4-Epitetracycline, an epimer of Tetracycline. Tetracycline is a broad-spectrum antibacterial and selection agent. We also offer:4-Epitetracycline Hydrochloride, EvoPure®...