SKU: S084  / 
    CAS Number: 131929-60-7

    Spinosyn A

    $230.21 - $805.73
    Spinosyn A is the major component of a complex of unusual, hydrophobic macrocyclic lactones isolated from Saccharopolyspora spinosa in 1991. The 12-membered macrocyclic lactone is fused to form a rare 12-5-6-5 tetracyclic ring system, with the macrocycle and the terminal cyclopentane bearing glycosides. Spinosyn A is a potent insecticide for crop pathogens and ectoparasite control on animals. The spinosyns have a unique mechanism of action involving disruption of nicotinic acetylcholine receptors.

    Spinosyn A is soluble in ethanol, methanol, DMF and DMSO. 
    ReferencesA 83543A-D, unique fermentation-derived tetracyclic macrolides. Kirst H.A. et al. Tetrahedron Lett. 1991, 32, 4839.

    The spinosyn family of insecticides: realizing the potential of natural products research. Kirst H.A. J. Antibiot. 2010, 63, 101.