SKU: K018  / 
    CAS Number: 92090-94-3

    Kazusamycin A

    $371.50 - $1,296.00

    Kazusamycin A is a minor member of the Leptomycin complex isolated from some Streptomyces species. It is a hydroxylated analog of Leptomycin B, a nuclear export inhibitor. It is similar to Leptomycins A and B in physico-chemical and biological characteristics. It has anti-cancer properties.  It can inhibit nuclear export and Rev translocation, a gene product in HIV-1 genome, at nanomolar concentrations.

    Kazusamycin A is soluble in ethanol, methanol, ethyl acetate, acetone, chloroform and benzene, practically insoluble in water, and unstable in DMSO. 

    We also offer:

    • Kazusamycin B (K019)
    • Leptomycin A (L020)
    • Leptomycin B (L004)