Drimendiol is the sesquiterpene dialcohol of polygodial, found in a number of plant species native to Australia and New
Zealand. More recently, drimendiol was prepared from polygodial isolated from Tasmannia lanceolata by Smith and colleagues at the University of Tasmania, Australia. Drimendiol's bioactivity has received little attention but it is reported as a quorum sensing inhibitor.
Hemquet MGL et al (2017) Identification of a drimenol synthase and drimenol oxidase from Persicaria hydropiper, involved in the biosynthesis of insect deterrent drimanes. Plant J. 90:1052
Just J et al (2015) Practical isolation of polygodial from Tasmannia lanceolata:A viable scaffold for synthesis. Org.Biomol. Chem. 13:11200
Paza C et al (2013) Drimendiol, a drimane sesquiterpene with quorum sensing inhibition activity. Nat. Prod. Commun. 8:147