SKU: K006  / 
    CAS Number: 65277-42-1


    $120.36 - $521.96

    Ketoconazole is an insoluble imidazole antimycotic compound.

    This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions.

    Mechanism of ActionKetoconazole increases cell permeability by inhibiting enzymes involved in ergosterol synthesis. The increase of permeability has a toxic effect on the fungi and leads to cell death.
    SpectrumKetoconazole is a broad spectrum antifungal agent targeting a wide variety of fungal cell membranes.
    Molecular FormulaC26H28Cl2N4O4

    Rice L.B. and Ghannoum M.A.. "Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance. Clinical Microbiology Reviews (1999): 501-17.

    Van Tyle, J. H. "Ketoconazole. Mechanism of Action, Spectrum of Activity, Pharmacokinetics, Drug Interactions, Adverse Reactions and Therapeutic Use."PubMed (1984): 343-73.