SKU: M081  / 
    CAS Number: 20449-79-0


    Melittin is the principal toxic component of honey bee venom from Apis mellifera, making up 50% of its dry weight. It is a 26 residue long antimicrobial peptide has an α-helical conformation, and associates strongly with membranes. It has demonstrated antibacterial, antiviral, anti-inflammatory activities. It has also undergone research as a cancer treatment for its aparent cell growth inhibition and apoptosis promoting activities.

    Melittin is water soluble.

    This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions. 
    Molecular FormulaC131H229N39O31
    ReferencesLeandro, L. F., Mendes, C. A., Casemiro, L. A., Vinholis, A. H., Cunha, W. R., Almeida, R. D., & Martins, C. H. (2015). Antimicrobial activity of apitoxin, melittin and phospholipase A2 of honey bee (Apis mellifera) venom against oral pathogens. Anais Da Academia Brasileira De Ciências, 87(1), 147-155. doi:10.1590/0001-3765201520130511

    Raghuraman, H., & Chattopadhyay, A. (2006). Melittin: A Membrane-active Peptide with Diverse Functions. Bioscience Reports, 27(4-5), 189-223. doi:10.1007/s10540-006-9030-z