Minocycline is a broad-spectrum, second-generation tetracycline. Like other tetracyclines, Minocycline shows broad spectrum antibacterial and antiprotozoan activity. It was patented in 1961 (American cyanamid) and synthesized in 1966 (Lederle Labs). Minocycline has been found to have many non-antibiotic biological effects in experimental models with inflammatory basis, autoimmune properties, and neuroprotection. It is an indirect inhibitor of inducible nitric oxide synthase. Minocycline is soluble in ethanol, methanol, DMF or DMSO but has limited water solubility.
We also offer:
- Minocycline Hydrochloride (M008)