SKU: L020  / 
    CAS Number: 87081-36-5

    Leptomycin A

    $379.50 - $1,325.00

    Leptomycin A is an antifungal and methyl analog of Leptomycin B, is a minor component of the Leptomycin complex produced by selected Streptomyces species. Leptomycin A, like Leptomycin B, is a potent inhibitor of the nuclear transport receptor exportin 1 (CRM1). The two may differ in exporter selectivity.  The compound is less potent than its analog, Leptomycin B.  Leptomycin A has antimicrobial activity against Schizosaccaromyces pombe and Mucor rouxianus. 

    Leptomycin A is soluble in ethanol and methanol, practically insoluble in water, and unstable in DMSO.

    We also offer:

    • Leptomycin B (L004)
    • Kazusamycin A (K018)
    • Kazusamycin B (K019)