Anhydroerythromycin A (Erythromycin impurity D) is an impurity found in Erythromycin and is formed from the acid-catalyzed degradation of Erythromycin A under in vitro and in vivo conditions. It has negligible antibacterial activity but can be used as a reference standard. Anhydroerythromycin A is soluble in chloroform and sparingly soluble in water.
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