SKU: D053  / 
    CAS Number: 59865-15-5

    Dihydrocyclosporin A

    $126.36 - $442.23

    Dihydrocyclosporin A is co-metabolite of Cyclosporin A. Dihydrocyclosporin A has no immunosuppressant activity and has found use as a control to determine the role of Cyclosporin A  in pharmacology, particularly for parasitic infections. Dihydrocyclosporin A is soluble in ethanol, methanol, DMF and DMSO. 

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    Eukaryotic Cell Culture Applications Dihydrocyclosporin A is used as a control to determine the role of Cyclosporin A in pharmacology, particularly in parasitic infection.
    Molecular Formula C62H113N11O12
    References Meier GP et al (1990) Isolation and identification of a novel human metabolite of Cyclosporin A: dihydro-CsA M17. Drug Metab Dispos. 18:68

    Chappell LH et al (1987) Dosage, timing, and route of administration of Cyclosporin A and nonimmunosuppressive derivatives of dihydrocyclosporin A and Cyclosporin C against Schistosoma mansoni in vivo and in vitro. Antimicrob Agents Chemother. 31:1567

    Chappell LH et al (1989) Action of Cyclosporin A on the tapeworms Hymenolepis microstoma, H. diminuta and Mesocestoides corti in vivo. Parasitology. 98:291