SKU: F004  / 
    CAS Number: 67-45-8

    Furazolidone

    $50.59 - $102.41

    Furazolidone is a synthetic nitrofuran antibiotic and monoamine oxidase inhibitor (MAOI) with antiprotozoal and antibacterial activity. It is effective against a range of Gram-positive and Gram-negative bacteria and is often used to treat gastrointestinal infections.

    Mechanism of Action Furazolidone targets bacterial DNA to induce crosslinks which lead to an increased mutation rate or prevents complete DNA replication.
    Spectrum Furazolidone is a broad-spectrum antibiotic targeting bacteria responsible for gastrointestinal infections.
    Microbiology Applications Furazolidone is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram-positive and Gram-negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients.  Representative MIC values include:
    • Treponema hyodysenteriae 0.1 µg/mL – 1.56 µg/mL
    • For a complete list of furazolidone MIC values, click here.
    Molecular Formula C8H7N3O5
    References

    Chatterjee SN (1979)  Mechanism of action of Furazolidone: Inter-strand cross-linking in DNA & liquid holding recovery of Vibrio Cholerae Cells." Indian J. Biochem. and Biophys. 16 (3):125-30

    MIC Lactobacillus reuteri| 90|| Treponema hyodysenteriae | ≤0.1 - 1.56 || Vibrio harveyi| 12.5||