Erythromycin A N-oxide is a minor analog of the Erythromycin complex. The N-oxide is a facile metabolite formed in vivo which can revert to Erythromycin A under reducing conditions. Despite its synthetic preparation in the 1950s, the biological activity of eEythromycin A N-oxide has not been extensively studied.
Erythromycin A N-oxide is soluble in water, ethanol, methanol, DMF and DMSO.
Erythromycin A N-oxide is soluble in water, ethanol, methanol, DMF and DMSO.
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| References | Beran M et al (1991) Isolation of erythromycin A N-oxide and pseudoerythromycin A hemiketal from fermentation broth of Saccharopolyspora erythraea by thin-layer and high-performance liquid chromatography. Chromatography A 558:265 Bluauerova M. et al (1991) Cosynthesis of erythromycin A N-oxide by mutants of Saccharopolyspora erythraea blocked in erythromycin production. Folia Microbiol. 36:533 Flynn EH et al (1954) Erythromycin. I. Properties and degradation studies. J. Am. Chem. Soc. 76:3121 |
