SKU: E054  / 
    CAS Number: 992-65-4

    Erythromycin A N-oxide

    $86.36 - $302.23
    Erythromycin A N-oxide is a minor analog of the Erythromycin complex.  The N-oxide is a facile metabolite formed in vivo which can revert to Erythromycin A under reducing conditions. Despite its synthetic preparation in the 1950s, the biological activity of eEythromycin A N-oxide has not been extensively studied.

    Erythromycin A N-oxide is soluble in water, ethanol, methanol, DMF and DMSO.

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    ReferencesBeran M et al (1991) Isolation of erythromycin A N-oxide and pseudoerythromycin A hemiketal from fermentation broth of Saccharopolyspora erythraea by thin-layer and high-performance liquid chromatography. Chromatography A 558:265

    Bluauerova M. et al (1991) Cosynthesis of erythromycin A N-oxide by mutants of Saccharopolyspora erythraea blocked in erythromycin production. Folia Microbiol. 36:533

    Flynn EH et al (1954) Erythromycin. I. Properties and degradation studies. J. Am. Chem. Soc. 76:3121