10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity.
10'-Desmethoxystreptonigrin is soluble in ethanol, methanol, DMF and DMSO.
10'-Desmethoxystreptonigrin is soluble in ethanol, methanol, DMF and DMSO.
| Molecular Formula | C24H20N4O7 |
| References | 10'-desmethyloxystreptonigrin, a novel analog of streptonigrin. Liu W.C. et al. J. Antibiot. 1992, 45, 454. |
