Gene Selection Antibiotics

Coumermycin A1

Coumermycin A1 is a natural, broad-spectrum aminocoumarin and DNA gyrase inhibitor.  Coumermycin A1 was developed in the early 1970s by Roche Applied Science.  Coumarin glycosides are aromatic compounds containing a carbohydrate glycosidically...

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Ceftazidime Hydrochloride

Ceftazidime Hydrochloride is a non-toxic hydrochloride salt derivative of Ceftazidime, a broad-spectrum, third-generation, β-lactam cephalosporin that interferes with bacterial cell wall synthesis.  Patented in 1979 by Glaxo Group, it came into...

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Nourseothricin (Streptothricin) Sulfate

Nourseothricin (Streptothricin) Sulfate is a broad-spectrum Streptothricin antibiotic and peptidyl nucleoside derived from Streptomyces noursei.  It is used as a selection agent for genetically modified bacteria, yeast, plants, fungi, and protozoa...

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Bleomycin A5 Hydrochloride

Bleomycin A5 Hydrochloride is part of the Bleomycin complex.  It is an anti-neoplastic glycoprotein antibiotic used in cancer research.  The Bleomycins were originally isolated for their broad spectrum antibacterial activity.We also offer:...

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Puromycin

Puromycin is an aminonucleoside antibiotic with anti-trypanosomal and antineoplastic properties.  It was isolated from Streptomyces alboniger in the 1950s. Puromycin is used in cell biology to select for mammalian cell lines that have been...

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Chloramphenicol Succinate

Chloramphenicol Succinate is prepared by acylation of chloramphenicol with succinic anhydride to provide a water soluble pro-drug. Chloramphenicol is released in the presence of succinate dehydrogenase in the human gut. Chloramphenicol Succinate is...

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Chloramphenicol Succinate Sodium

Chloramphenicol Succinate Sodium is prepared from Chloramphenicol succinate using the free carboxylic acid form which ionises and readily forms in weak sodium hydroxide solutions. The sodium salt is the preferred formulation in pharma research, providing...

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Chloramphenicol Palmitate

Chloramphenicol Palmitate is prepared by acylation of Chloramphenicol with palmitic acid. Chloramphenicol Palmitate is significantly less active than Chloramphenicol but acts as a prodrug, being readily hydrolysed by acid and esterase in the human gut to...

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Blasticidin S Hydrochloride

Blasticidin S Hydrochloride (syn: Blasticidin S HCl) is a peptidyl nucleoside produced by several species of Streptomyces that was first isolated from S. griseochromogenes in 1958. Blasticidin S inhibits protein synthesis and is active...

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G418 Disulfate (Low Endotoxin)

G418 Disulfate (Low Endotoxin) has a strict endotoxin content of ≤ 1 EU/mg. G418 Disulfate, an aminoglycoside antibiotic originally isolated from Micromonospora rhodorangea, is routinely used for gene selection in cell culture. The presence of...

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G418 Disulfate

G418 Disulfate (syn: Geneticin; G418 Sulfate) is an aminoglycoside antibiotic isolated from Micromonospora rhodorangea and is closely related to Gentamicin B1.  G418 is an analog of Neomycin Sulfate and has a similar mechanism to Neomycin.  It...

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Blasticidin S

Blasticidin S is a peptidyl nucleoside produced by several species of Streptomyces that was first isolated from S. griseochromogenes in 1958.  Blasticidin S inhibits protein synthesis and is active against bacteria, fungi, nematodes, and tumor cells...

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