Antimicrobials

1,6-dimethoxyphenazine

1,6-Dimethoxyphenazine is a simple phenazine produced by several species of Streptomyces. Dimethoxyphenazine is a weakly active antibacterial metabolite with activity against mycobacteria. Dimethoxyphenazine and related phenazines are important...

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1-(3,4-Dichlorophenyl)-3-(1,3-thiazol-2-yl)thiourea

1-(3,4-Dichlorophenyl)-3-(1,3-thiazol-2-yl)thiourea is a thiourea derivative synthesized from 1,3-thiazole. The 1,3-thiazoles are an important group of compounds due to their wide range of applications  in biopharma.  The thioureas have been...

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1-(3-Chloro-4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea

1-(3-Chloro-4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea is a thiourea derivative (specifically the 3-chloro-4-fluorophenyl-substituted derivative) synthesized from 1,3-thiazole. The 1,3-thiazoles are an important group of compounds due to...

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1-Cyclohexyl-3-(1,3-thiazole-2-yl)thiourea

1-Cycolohexyl-3-(1,3-thiazole-2-yl)thiourea is a thiourea derivative.  The 1,3-thiazoles are an important group of compounds due to their wide range of applications in biopharma.  The thioureas have been described as the most useful class...

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10'-desmethoxystreptonigrin

10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has...

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4-epianhydrochlortetracycline hydrochloride

4-epianhydrochlortetracycline (chlortetracycline impurity K) is a secondary degradation product formed by dehydration of epichlortetracycline at the C6 position to aromatise the B ring. 4-epianhydrochlortetracycline is an important standard for...

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4-Epichlortetracycline Hydrochloride

Epichlortetracycline is a degradation product of chlorotetracycline formed by acid-catalysed isomerisation of the dimethylamino group at C4. Epichlortetracycline exhibits little antibiotic activity but its abundance is indicative of poor storage and...

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4-epitetracycline ammonium salt, EvoPure®

4-epitetracycline ammonium salt, EvoPure® is a highly purified version of 4-Epitetracycline, an epimer of Tetracycline. Tetracycline is a broad-spectrum antibacterial and selection agent. We also offer:4-Epitetracycline HCl, EvoPure® (T053)...

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6-Aminopenicillanic acid

6-Aminopenicillanic Acid or (+)-6-Aminopenicillanic Acid (6-APA) is an organic dipeptide and the  chemical core or "nucleus" of penicillin antibiotics.  It was discovered in 1958  (Beecham Group, UK).  It is produced from Penicillin...

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7-Aminocephalosporanic Acid

7-Aminocephalosporanic Acid (7-ACA) is a key intermediate in the production of a wide variety of semisynthetic Cephalosporin antibiotics.  It is an inhibitor of bacterial (S. aureus) β-lactamase.  It is derived from mild acid...

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A 26771B

A 26771B is a 16-membered macrocyclic lactone isolated from Penicillium turbatum patented and then published by Eli Lilly and Co. in 1975. A 26771B is closely related to the berkeleylactones, recently reported as antibiotics derived from a cofermentation...

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A 39183A

A 39183A is factor A from the A-39183 antibiotic complex. The A-39183 antibiotic complex was isolated from the aerobic fermentation of Streptomyces (strain NRRL 12049) by Eli Lilly in 1979.  This complex contains closely-related factors A, B, C, D,...

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