Cellocidin is a small neutral alkyne produced by a number of Streptomyces species, first discovered by Suzuki and colleagues in 1958. Cellocidin has a broad antibacterial, antifungal and antitumor profile due to its ability to react with endogenous thiols like cysteine and glutathione. Cellocidin occurs as a weak active in many bioassays using actinomycete crude extracts and is thus a useful standard for chemical and bioassay dereplication.
Cellocidin is soluble in ethanol, methanol, DMF and DMSO.
Cellocidin is soluble in ethanol, methanol, DMF and DMSO.
| Molecular Formula | C4H4N2O2 |
| References | Cellocidin, a new antibiotic. Suzuki S. et al. J. Antibiot. 1958, 11, 81. The structure of cellocidin. Suzuki S. & Okuma K. J. Antibiot. 1958, 11, 84. Antagonistic mechanism of sulfhydryl compounds on cellocidin activity. Yoneyama K. et al. J. Antibiot. 1978, 31, 065. |