Meleagrin is an alkaloid with antitumor and antibiotic activity, isolated from a number of species of Penicillium. Meleagrin is a common taxonomic marker for fungal contamination of foodstuffs. Note that meleagrin, the fungal metabolite, should not be confused with the low molecular weight protein, also meleagrin.
Meleagrin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Meleagrin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
| Mechanism of Action | Despite its wide detection in the environment, the mode of action and bioprofile has not been extensively reported. |
| Molecular Formula | C23H23N5O4 |
| References | Isolation of radicicol from Penicillium luteo-aurantium, and meleagrin, a new metabolite from Penicillium meleagrinum. Nozawa K. & Nakajima S. J. Nat. Prod. 1979, 42, 374. Production of mycotoxins on artificially and naturally infested building materials. Nielsen K.F. et al. Mycopathologia 1999, 145, 43. Mass spectrometry-based chemotaxonomic classification of Penicillium species (P. echinulatum, P. expansum, P. solitum, and P. oxalicum) and its correlation with antioxidant activity. Kim H.Y. J. Microbiol. Methods 2012, 90, 327. |