Setomimycin is a rare 9,9'-bianthryl antibiotic first isolated from a strain of Streptomyces pseudovenezuelae by Omura and colleagues at the Kitasato Institute, Japan, in 1978. Setomimycin is active against Gram positive bacteria, including mycobacteria, and has antitumor activity both in vitro and in vivo. Limited access has restricted further research on this metabolite.
Setomimycin is soluble in ethanol, methanol, DMF and DMSO.
Setomimycin is soluble in ethanol, methanol, DMF and DMSO.
| References | A new antibiotic, setomimycin, produced by a strain of Streptomyces. Omura S. et al. J. Antibiot. 1978, 31, 1091. Structure and biosynthesis of setomimycin, a novel 9,9'-bianthryl antibiotic. Kakinuma K. et al. J. Am. Chem. Soc. 1980, 102, 7493. |