1,6-Dimethoxyphenazine is a simple phenazine produced by several species of Streptomyces. Dimethoxyphenazine is a weakly active antibacterial metabolite with activity against mycobacteria. Dimethoxyphenazine and related phenazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives.
1,6-Dimethoxyphenazine is soluble in ethanol, methanol, DMF and DMSO.
1,6-Dimethoxyphenazine is soluble in ethanol, methanol, DMF and DMSO.
Molecular Formula | C14H12N2O2 |
References | Phenazines, phenoxazinones and dioxopiperazines from Streptomyces thioluteus. Gerber N.N. J. Org. Chem. 1967, 32, 4055. Phenazine natural products: Biosynthesis, synthetic analogues, and biological activity. Laursen J.B. & Nielsen J. Chem. Rev. 2004, 104, 1663. |