21-Hydroxyoligomycin A is a rare member of the Oligomycin class, isolated as a co-metabolite of nemadectin, hence it was originally named Nemadectin omega. Only limited literature references are available. In-house testing suggests that 21-Hydroxyoligomycin has a more selective action against mammalian tumor cell lines than Oligomycin A, exhibiting only weak antifungal and nematocidal activity. 21-Hydroxyoligomycin A can Inhibit K-Ras plasma membrane localization and is therefore a putative anti-cancer agent.
21-Hydroxyoligomycin A is soluble in ethanol, methanol, DMF and DMSO but practically insoluble in water.
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