Lamivudine (3TC) is a cytidine analog and antiretroviral medication commonly used to treat HIV and hepatitis B infections.
Mechanism of Action | Lamivudine inhibits HIV reverse transcriptase and terminates DNA synthesis by competing for incorporation into viral DNA. |
Spectrum | Lamivudine targets retroviruses hepatitis B virus (HBV) and human immunodeficiency virus (HIV). |
Impurity Profile | Lamivudine Enantiomer: Not more than 0.3% |
Molecular Formula | C8H11N3O3S |
Residual Solvents | Alcohol: Not more than 0.2% Isopropyl Acetate: Not more than 0.2% Methanol: Not more than 0.1% Triethylamine: Not more than 0.1% Total Residual Solvents: Not more than 0.3% |
References | Balzarini, Jan, Lieve Naesens, and Erik De Clercq. "New Antivirals — Mechanism of Action and Resistance Development." Current Opinion in Microbiology 1.5 (1998): 535-46. Web. |