SKU: A144  / 
    CAS Number: 1420477-60-6

    Acalabrutinib

    $162.63
    Acalabrutinib is a highly selective, irreversible inhibitor of Bruton's tyrosine kinase (BTK), and is being considered for use in the treatment of relapsed chronic lymphoid leukemia. Mutations in BTK result in a variety of B-cell related malignancies, as it upsets the B cell's signalling pathways.
    Molecular FormulaC26H23N7O2
    ReferencesWu, J., Zhang, M., & Liu, D. (2016). Acalabrutinib (ACP-196): A selective second-generation BTK inhibitor. Journal of Hematology & Oncology, 9(1). doi:10.1186/s13045-016-0250-9