Artemisinin is a sesquiterpene lactone compound with anti-malarial activity against cerebral malaria causing and drug-resistant strains of Plasmodium falciparum. Artemisinin and some of its derivatives have anti-tumor properties and are effective against other clinically significant parasites.
|Mechanism of Action||The mechanism of action of artemisinin has not been proven and is not fully understood. A recent study identified 124 artemisinin binding sites in Plasmodium falciparum suggesting multiple mechanisms of action.|
|References||Walters, Michael. "Faculty of 1000 Evaluation for Haem-activated Promiscuous Targeting of Artemisinin in Plasmodium Falciparum." F1000 - Post-publication Peer Review of the Biomedical Literature 6 (2015)|
Klayman, D. "Qinghaosu (artemisinin): An Antimalarial Drug from China."Science 228.4703 (1985): 1049-055.