Asunaprevir is a tripeptidic acylsulfonamide antiviral compound and is currently being used as an experimental drug fro the treatment of hepatitis C.
| Mechanism of Action | Asunaprevir targets and inhibits the NS3 protease enzyme which is essential for HCV replication. |
| Impurity Profile | Related substances: Any impurity: Not more than 0.3% Total impurities: Not more than 1.0% |
| Molecular Formula | C35H46ClN5O9S |
| Residual Solvents | Tetrahydrofuran: Not more than 0.072% Ethanol: Not more than 0.5% Ethyl Acetate: Not more than 0.5% |
| References | Gentile, Ivan, Antonio Riccardo Buonomo, Emanuela Zappulo, Giuseppina Minei, Filomena Morisco, Francesco Borrelli, Nicola Coppola, and Guglielmo Borgia. "Asunaprevir, a Protease Inhibitor for the Treatment of Hepatitis C Infection." Therapeutics and Clinical Risk Management TCRM (2014): 493. |