Bafilomycin B1 is a member of a potent family of macrocyclic lactones. Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential agent for treating osteoporosis.
Bafilomycin B1 is soluble in ethanol, methanol, DMF and DMSO.
Bafilomycin B1 is soluble in ethanol, methanol, DMF and DMSO.
| Mechanism of Action | Bafilomycin A1 is an inhibitor of vacuolar-type ATPase. |
| References | Bafilolides, Potent Inhibitors of the Motility and Development of the Free-Living Stages of Parasitic Nematodes. Lacey E. et al. Int. J. Parasitol. 1995, 25, 349. Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of osteolysis. Xu J. et al. Histol. Histopathol. 2007, 22, 443. |
