Bafilomycin D is a member of a potent family of macrocyclic lactones. Bafilomycin D contains the ring-opened side chain and is a much more stable analogue of bafilomycin A1. Limited availability has restricted a more in depth investigation of this metabolite.
Bafilomycin D is soluble in ethanol, methanol, DMF and DMSO.
Bafilomycin D is soluble in ethanol, methanol, DMF and DMSO.
| Mechanism of Action | Bafilomycin D is an inhibitor of vacuolar-type ATPase. |
| References | The structure of novel insecticidal macrolides: bafilomycin D and E, and oxhygrolidin. Kretschmer A. et al. , Agric. Biol. Chem. 1985, 49, 2509 Bafilolides, Potent Inhibitors of the Motility and Development of the Free-Living Stages of Parasitic Nematodes. Lacey E. et al. , Int. J. Parasitol. 1995, 25, 349. |
