Bithionol is an anti-parasitic drug and has recently been found to have anti-ovarian cancer properties. In one study, bithionol inhibited all tested ovarian cancer cell lines with IC
50 values from 19 µM - 60 µM.
| Mechanism of Action | The mechanism of action of bithionol is not completely understood but is thought to inhibit cancer cell growth by reactive oxygen species generation, NF-kB inhibition and autotaxin inhibition. |
| Molecular Formula | C12H6Cl4O2S |
| References | Ayyagari, Vijayalakshmi N., and Laurent Brard. "Bithionol Inhibits Ovarian Cancer Cell Growth In Vitro - Studies on Mechanism(s) of Action." BMC Cancer 14.1 (2014): 61. |
