Bithionol is an anti-parasitic drug and has recently been found to have anti-ovarian cancer properties. In one study, bithionol inhibited all tested ovarian cancer cell lines with IC50
values from 19 µM - 60 µM.
|Mechanism of Action||The mechanism of action of bithionol is not completely understood but is thought to inhibit cancer cell growth by reactive oxygen species generation, NF-kB inhibition and autotaxin inhibition.|
|References||Ayyagari, Vijayalakshmi N., and Laurent Brard. "Bithionol Inhibits Ovarian Cancer Cell Growth In Vitro - Studies on Mechanism(s) of Action." BMC Cancer 14.1 (2014): 61.|