SKU: D078  / 
    CAS Number: 87205-99-0

    Dihydrotanshinone I

    $122.54 - $432.21
    Dihydrotanshinone I is one of many bioactive products isolated from Salvia miltiorrhiza, a well-known traditional Chinese medicinal plant. It's primary promise lies in its anticancer activity, but it has been found to be active against gram-positive bacteria as well.

    This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions.
     
    Mechanism of ActionDihydrotanshinone I initiates programmed cell death by activating caspases 3 and 9, which contribute to the degredation of cellular components.
    ReferencesLee, D., Lee, S., Noh, J., & Hong, S. (1999). Antibacterial Activities of Cryptotanshinone and Dihydrotanshinone I from a Medicinal Herb, Salvia miltiorrhiza Bunge. Bioscience, Biotechnology, and Biochemistry, 63(12), 2236-2239. doi:10.1271/bbb.63.2236

    Lee, D., & Lee, S. (2000). Biological activity of dihydrotanshinone I: Effect on apoptosis. Journal of Bioscience and Bioengineering, 89(3), 292-293. doi:10.1016/s1389-1723(00)88838-6

    Wang, L., Hu, T., Shen, J., Zhang, L., Chan, R. L., Lu, L., . . . Wu, W. K. (2015). Dihydrotanshinone I induced apoptosis and autophagy through caspase dependent pathway in colon cancer. Phytomedicine, 22(12), 1079-1087. doi:10.1016/j.phymed.2015.08.009