(+)-Epoxysuberosin is a coumarin isolated from Hesperethusa crenulata by Nayar and Bhan from Regional Research
Laboratory, India, in 1972. More recently, Smith and Bissember at the University of Tasmania, Australia, isolated
epoxysuberosin from the native fuchsia, Correa reflexa, using pressurized hot water extraction. Epoxysuberosin is active
against leishmania, but its biological activity is largely unexplored.
| Molecular Formula | C15H16O4 |
| References | Deans BJ et al (2017) Pressurized hot water extraction as a viable bioprospecting tool: isolation of coumarin natural products from previously unexamined Correa (Rutaceae) species. Chemistry Select 2: 2433 Guz NR et al (2001) New coumarins from Harbouria trachypleura: Isolation and synthesis. Tet. Lett. 42:6491 Nayar MNS and Bhan MK (1972) Coumarins and other constituents of Hesperethusa crenulata. Phytochemistry 11:3331 Sajjadi SE et al (2016) Antileishmanial activity of prenylated coumarins isolated from Ferulago angulata and Prangos asperula. Res. Pharm. Sci. 11:324 |