Ethambutol is a unique slightly soluble (7.58 mg/mL) antitubercular antibiotic which inhibits cell wall formation in Mycobacterium species.
|Mechanism of Action
|Ethambutol inactivates arabinosyl transferase, an enzyme responsible for transporting mycolic acids to the cell wall. Without this enzyme, cell permeability is increased leaving the oraganism vulnerable to toxic matter.
|Ethambutol targets primarily species of the Mycobacterium genus including Mycobacterium tuberculosis.