Heronamide C is an unusual polyene macrocyclic lactam containing two isolated tetraene and triene chromophores. Heronamide C induces a unique reversible vacuolisation of mammalian tumor cells.
Heronamide C is soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.
Heronamide C is soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.
| Mechanism of Action | The mechanism of action of heronamide C's antitumor activity is not yet known. |
| References | Heronamides A – C, new polyketide macrolactams from an Australian marine-derived Streptomyces sp. A biosynthetic case for synchronized tandem electrocyclization. Ritesh R. et al. Org. Biomol. Chem. 2010, 8, 4682. |
