SKU: H060  / 
    CAS Number: C33H38N6

    Hodgkinsine

    $207.00 - $825.00

    The hodgkinsines are indole alkaloids from Hodgkinsonia frutescens (family Rubiaceae) containing three linked tryptamine units. Hodkinsine was first reported by Ritchie et al (University of Sydney) in 1961. Hodgkinsine shows potent dose-​dependent analgesic activity against capsaicin-​induced pain, with low affinity for mu opioid receptors. Hodgkinsine has a broad bioprofile with potent antimicrobial activity, antifungal and cytotoxic activity. Hodgkinsine has antiviral activity against DNA viruses and is a platelet aggregation inhibitor.

    Molecular Formula  C33H38N6
    References

    Amando TA et al (2000)  Antinociception profile of hodgkinsine. Planta Med. 66:770

    Anet EFLJ et al (1961)  Hodgkinsine, the alkaloid of Hodgkinsonia frutescens. Anet E.F.L.J. et al. Aust. J. Chem. 14:173

    Saad HE et al (1995)  Biological activities of pyrrolidinoindoline alkaloids from Calycodendron milnei Planta Med. 61:313