SKU: H035  / 
    CAS Number: 127-07-1

    Hydroxyurea

    ¥17,572.23 - ¥64,882.08

    Hydroxyurea is an antineoplastic chemotherapeutic compound used in sickle cell anemia studies and cancer research, including leukemia, skin cancer, and ovarian cancers.

    Hydroxyurea is freely soluble in water.

    Mechanism of Action Hydroxyurea targets the ribonucleotide reductase essential to DNA synthesis, and arrests the cell cycle at S-phase.
    References Segal JB, Strouse JJ, Beach MC, et al. Hydroxyurea for the Treatment of Sickle Cell Disease. Rockville (MD): Agency for Healthcare Research and Quality (US); 2008 Feb. (Evidence Reports/Technology Assessments, No. 165.) 1, Introduction. Available from: http://www.ncbi.nlm.nih.gov/books/NBK38503/