Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and Gram negative bacteria, including MRSA strains, also displaying antitumor activity. Kendomycin is a potent endothelin receptor agonist and demonstrates antiosteoporotic activity.
Kendomycin is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Kendomycin is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
| References | Structure and biosynthesis of kendomycin, a carboxylic ansa-compound from Streptomyces. Bode H.B & Zeeck A. 2000. J. Chem. Soc., Perkin Trans. I 323-328. Antiosteoporotic compound. Su M.H. et al. 1998. US Patent 5728727. |