Lincomycin is a lincosamide first isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. This class of antibacterial contains a rare amino acid (4-propyl-N-methylprolin) coupled to an equally rare aminomethylthio-octopyranoside sugar. Lincomycin is often incorrectly considered an aminoglycoside but it actually shares little or no structural similarity. It is effective for Gram-positive bacteria and disrupts protein synthesis.
Lincomycin is soluble in ethanol, methanol, DMF and DMSO. Lincomycin is slightly soluble in water.
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