SKU: L052  / 
    CAS Number: 545-47-1

    Lupeol

    $61.74 - $216.09

    Lupeol is a pentacyclic lupane triterpene produced by various fruits, vegetables and other plants, first isolated in 1898 and published in 1907. Lupeol is reported to have very diverse biological effects, including anti-inflammatory, anti-diabetic, hepatoprotective and cardiovascular activities. Lupeol exerts antitumor activity via downregulation of TNF-α and reduction of downstream effector levels of VEGFR-2 signaling. Lupeol attenuates protein expression of NFKB1, COX-2, and CASP3 in bovine embryos in vitro.

    Molecular Formula  C30H50O
    References

    Jungfleisch E and Leroux H (1907)  Lupeol 144:1435

    Kangsamaksin T. et al (2017)  Lupeol and stigmasterol suppress tumor angiogenesis and inhibit cholangiocarcinoma growth in mice via downregulation of tumor necrosis factor-α. PLoS One 12.

    Khan I et al (2018)  Lupeol supplementation improves the developmental competence of bovine embryos in vitro. Theriogenol. 107:203

    Tsai FS et al (2016)  Lupeol and its role in chronic diseases. Adv. Exp. Med. Biol 929:145