Menadione Sodium Bisulfite (syn: Vitamin K3) is the metabolic precursor of the vitamin K2 in mammals. It is a possible anticancer agent, causing induction of apoptosis. It is soluble in aqueous solution.
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- Menadione (M079)
|References||Hirota Y et al (2013) Menadione (Vitamin K3) Is a catabolic product of oral phylloquinone (Vitamin K1) in the intestine and a circulating precursor of tissue Menaquinone-4 (Vitamin K2) in Rats. J. Biol. Chem. 288(46): 33071-33080
Suresh S, Raghu D, and Karunagaran D (2013) Menadione (Vitamin K3) induces apoptosis of human oral cancer cells and reduces their metastatic potential by modulating the expression of epithelial to mesenchymal transition markers and inhibiting migration. Asian Pac. J. Cancer Prev.14(9):5461-5465