Mer-NF5003E is a sesquiterpenoid mycotoxin isolated from Stachybotrys strains, first published in 1994 as an avian
myeloblastosis virus (AMV) protease inhibitor. Mer-NF5003E is inactive against HIV due to host cell toxicity. An analogue, MerNF5003B has been isolated from fungal biomass and dust samples collected in a domestic facility and may be a useful
biomarker to assess exposure to potentially harmful S. chartarum contamination.
Dosen I et al (2016) Stachybotrys mycotoxins: from culture extracts to dust samples. Anal. Bioanal. Chem. 408:5513
Kaneta R et al (1994) Mer-NF5003B, E and F, novel sesquiterpenoids as avian myeloblastosis virus protease inhibitors produced by Stachybotrys sp. J. Antibiot. 47:727