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Detailed Description
CAS Number: 914-00-1
Molecular Formula: C22H22N2O8
Molecular Weight: 442.4
Mechanism of Action: Like all tetracyclines, methacycline acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.
Storage Conditions: -20°C
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Specifications
Appearance: Yellow to orange solid
Purity Level: >98% by HPLC
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References
References: 6-Methylenetetracyclines. I A new class of tetracycline antibiotics. Blackwood R.K. et al. J. Am. Chem. Soc. 1961, 83, 2773.
6-Methylenetetracyclines. III. Preparation and Properties. Blackwood R.K. et al. J. Am. Chem. Soc. 1963, 85, 3943.
A comparison of the in vitro and in vivo activity of methacycline and other tetracycline compounds. Chang T.W. & Weinstein L. Antibiot. Chemother. 1962, 12, 676.
Evaluation of methacycline, a new analogue of oxytetracycline. Limson B.M. & Guevara R. Curr. Ther. Res. Clin. Exp. 1963, 5, 249.
Methacycline is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
CAS Number: 914-00-1
Molecular Formula: C22H22N2O8
Molecular Weight: 442.4
Mechanism of Action: Like all tetracyclines, methacycline acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.
Storage Conditions: -20°C
Appearance: Yellow to orange solid
Purity Level: >98% by HPLC
References: 6-Methylenetetracyclines. I A new class of tetracycline antibiotics. Blackwood R.K. et al. J. Am. Chem. Soc. 1961, 83, 2773.
6-Methylenetetracyclines. III. Preparation and Properties. Blackwood R.K. et al. J. Am. Chem. Soc. 1963, 85, 3943.
A comparison of the in vitro and in vivo activity of methacycline and other tetracycline compounds. Chang T.W. & Weinstein L. Antibiot. Chemother. 1962, 12, 676.
Evaluation of methacycline, a new analogue of oxytetracycline. Limson B.M. & Guevara R. Curr. Ther. Res. Clin. Exp. 1963, 5, 249.