Multiflorenol is a triterpenoid found in the geranium family and other flowering plants, first isolated and the structure elucidated by Khastgir and Sengupta in 1961. Multiflorenol was subsequently isolated by Ritchie and Taylor from the Australian plant, Melicope octandra, in 1976. Multiflorenol inhibits histamine release induced by antigen-antibody reaction. Multiflorenol is inactive against HeLa human cervical, HL-60 human hepatoma, and SMMC-7721 human hepatoma cell lines.
Free AJ et al (1976) Some extractives of Melicope octandra (Rutaceae). Aust J. Chem. 29:695
Han X.N. et al (2013) New triterpenoids and other constituents from the fruits of Benincasa hispida (Thunb.) Cogn. J. Agric. Food Chem. 61:12692
Khastgir HN and Sengupta P (1961) Structure of multiflorenol. Chem. Indust. 1077
Yoshizumi S et al (1998) Medicinal foodstuffs. XI. Histamine release inhibitors from wax gourd, the fruits of Benincasa hispida Cogn. Yakuqaku Zasshi 118:188