Nosiheptide is a broad-spectrum bicyclic thiopeptide antibiotic produced by several species of actinomycetes (ie Streptomyces) and was first reported by Japanese researchers in 1970. It has a prolonged post-antibiotic effect in both nosocomial and community-acquired MRSA. Despite its long history in animal health research, Nosiheptide has not been extensively studied.
Nosiheptide is soluble in ethanol, methanol, DMF and DMSO.