SKU: P147  / 
    CAS Number: 1214268-60-6

    Penicinoline

    $288.12 - $1,008.42

    Penicinoline is an unusual quinolinone alkaloid isolated from a mangrove endophytic Penicillium species by researchers at the Key Laboratory of Marine Drugs in collaboration with Syngenta and first reported in 2010. Penicinoline posseses broad
    spectrum insecticidal activity and potent cytotoxic activity. In silico screening indicates that penicinoline inhibits EGFR 696-1022 T790M associated with non-small cell lung cancer.

    Molecular Formula  C14H10N2O3  
    References

    Shao C-L et al (2010)  Penicinoline, a new pyrrolyl 4-quinolinone alkaloid with an unprecedented ring system from an endophytic fungus Penicillium sp. Bioorg. Med. Chem. Lett. 20:3284

    Nand M et al (2016)  Virtual screening of natural compounds as inhibitors of EGFR 696-1022 T790M associated with non-small cell lung cancer. Bioinform. 12:311