SKU: P084  / 
    CAS Number: 13640-26-1

    Pimprinine

    $235.69 - $824.92
    Pimprinine is an indole alkaloid produced by many species of Streptomyces. More recently, pimprinine showed promising anticonvulsant activity in electric seizure threshold tests in mice, comparable to phenylhydantoin. Pimprinine also inhibits tremorine-induced tremors and analgesia in mice.

    Pimprinine is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
    Mechanism of ActionPimprinine is a potent inhibitor of monoamine oxidase.
    ReferencesIsolation, characterization and synthesis of pimprinine, pimprinethine and pimprinaphine, metabolites of Streptoverticillium olivoreticuli. Koyama Y. et al. Agri Biol Chem 1981, 45, 1285.

    Pimprinine, an extracellular alkaloid produced by Streptomyces CDRIL-312: fermentation, isolation and pharmacological activity. Naik S.R. et al. J Biotechnol. 2001, 88, 1.