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Sandramycin is a high molecular weight, symmetric, cyclic depsipeptide belonging to the quinomycin class produced by Kribbella sp.. Sandramycin has potent antitumor and antibacterial activity, and is thought to act by bis-intercalation of DNA...
Roquefortine E is an analogue of Roquefortine C, containing an additional isoprenyl unit on the imidazole similar to phenylhistin, a recently described antimitotic agent. Roquefortine E is a selective, albeit weakly active, antitumor agent.Roquefortine E...
Idelalisib is the free base version of the compound. It is a small molecule inhibitor of phosphoinositide 3-kinase. It also inhibits other class I P13K enzymes. It also inhibits several signaling pathways, including B-cell receptor...
Cetyltrimethyl Ammonium Bromide (CTAB) has a wide variety of bioactivity. In a laboratory setting, it is favored for the extraction of DNA from plants. CTAB is able to bind to polysaccharides and keep them from affecting the DNA purity. Due to its...
Reticulol is an isocoumarin metabolite produced by selected species of Streptomyces. Reticulol was first described as a potent inhibitor of cyclic nucleotide phosphodiesterase but more recent research has demonstrated a topoisomerase I inactivation...
Teleocidin A is a potent nematocide and acaricide produced by Streptoverticillium strains, first reported in 1960. Teleocidin A is a potent activator of protein kinase C, and also a tumor promoting agent and inducer of colony-stimulating factors. More...
Afatinib is an anilinoquinazoline derivative with a reactive acrylamide group. It is a tyrosine kinase inhibitor and blocks enzymatically active ErbB (proto-oncogene B of the avian erythroblastosis virus AEV-H strain) receptor family members...
Rucaparib Camsylate inhibits DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1), thus it belongs to a class known as PARP inhibitors, which have proven to have anti-cancer activity in a number of cancers. Rucaparib Camsylate is a...
Minocycline is a broad-spectrum, second-generation tetracycline. Like other tetracyclines, Minocycline shows broad spectrum antibacterial and antiprotozoan activity. It was patented in 1961 (American cyanamid) and synthesized in 1966 (Lederle Labs)...
Rucaparib phosphate is the phosphate salt of Rucaparib. It is a Poly(ADP-ribose) polymerase (PARP) inhibitor. PARP inhibitors have proven to have anti-cancer activity.Mechanism of ActionPARP inhibitors prevent the synthesis of poly-ADP ribose...
Rucaparib inhibits DNA repair enzyme poly-ADP ribose polymerase (PARP), thus it belongs to a class known as PARP inhibitors, which have proven to have anti-cancer activity. Mechanism of ActionPARP inhibitors prevent the synthesis of poly-ADP...
Reveromycin D is the isopentyl analogue and a minor component of the reveromycin complex, isolated from a Streptomyces sp.. Published information on reveromycin D suggests that it is more active than its straight chain analogue, reveromycin C.Reveromycin...
