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Elaiophylin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase and is synergistic with its co-metabolite, rapamycin, as an...
Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A has been investigated in clinical trials as an antitumor agent.Epothilone A is soluble in...
Dasatinib is multitarget kinase inhibitor used in the treatment of leukemia. Dasatinib's main targets are tyrosine kinase BCR/ABL, which works to provide the cancer cell with ATP at an uncontrolled...
Epothilone B is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum.Epothilone B is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.Mechanism of...
Oligomycin E (26-hydroxyoligomycin B) is a minor analog of a class of macrocyclic lactones isolated from selected strains of Streptomyces spp. It is a non-selective inhibitor of mitochondrial...
19,20-Epoxycytochalasin C is a major component of the cytochalasin complex. Although reported in the literature, there is no available biological data on the metabolite other than in-house data...
Citreoviridin is the dominant analogue of a family of tetraene mycotoxins with potent neurotoxic effects, produced by several species of Aspergillus and Penicillium. Citreoviridin inhibits...
19,20-Epoxycytochalasin D is a major component of the cytochalasin complex. Although reported in the literature, there is no available biological data on the metabolite other than in-house data...
Imatinib Mesylate is a tyrosine kinase inhibitor used primarily in cancer research studies focused on leukemia. Chronic Myeloid Leukemia (CML) cells contain a hybrid tyrosine kinase BCR/ABL that...
Nisin (Nisin A) is a natural bacteriocin polypeptide antibiotic known as a lantibiotic. It is a 34-amino acid polycyclic antibacterial peptide. It was isolated in the late 1930s from Lactococcus...
21-Hydroxyoligomycin A is a rare member of the Oligomycin class, isolated as a co-metabolite of nemadectin, hence it was originally named Nemadectin omega. Only limited literature references are...
Fostriecin is the most fully characterised member of a family of phosphate esters of a triene antibiotic. The antitumor potential of Fostriecin has attracted considerable interest, focused on its...