Steffimycin B is an anthracycline metabolite isolated from a Streptomyces sp. with antibacterial and antineoplastic properties. Crystallographic studies of binding to DNA suggest that it has a higher...
Lenvatinib, the free base form of the compound, is a small-molecule multityrosine kinase inhibitor that inhibits many receptor tyrosine kinases including vascular endothelial growth factor (VEGF),...
Sandramycin is a high molecular weight, symmetric, cyclic depsipeptide belonging to the quinomycin class produced by Kribbella sp.. Sandramycin has potent antitumor and antibacterial activity, and is...
Roquefortine E is an analogue of Roquefortine C, containing an additional isoprenyl unit on the imidazole similar to phenylhistin, a recently described antimitotic agent. Roquefortine E is a...
Idelalisib is the free base version of the compound. It is a small molecule inhibitor of phosphoinositide 3-kinase. It also inhibits other class I P13K enzymes. It also inhibits several signaling...
Cetyltrimethyl Ammonium Bromide (CTAB) has a wide variety of bioactivity. In a laboratory setting, it is favored for the extraction of DNA from plants. CTAB is able to bind to polysaccharides and...
Reticulol is an isocoumarin metabolite produced by selected species of Streptomyces. Reticulol was first described as a potent inhibitor of cyclic nucleotide phosphodiesterase but more recent...
Afatinib is an anilinoquinazoline derivative with a reactive acrylamide group. It is a tyrosine kinase inhibitor and blocks enzymatically active ErbB (proto-oncogene B of the avian erythroblastosis...
Rucaparib Camsylate inhibits DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1), thus it belongs to a class known as PARP inhibitors, which have proven to have anti-cancer activity in a number...
Minocycline is a broad-spectrum, second-generation tetracycline. Like other tetracyclines, Minocycline shows broad spectrum antibacterial and antiprotozoan activity. It was patented in 1961 (American...
Rucaparib phosphate is the phosphate salt of Rucaparib. It is a Poly(ADP-ribose) polymerase (PARP) inhibitor. PARP inhibitors have proven to have anti-cancer activity.Mechanism of ActionPARP...
Rucaparib inhibits DNA repair enzyme poly-ADP ribose polymerase (PARP), thus it belongs to a class known as PARP inhibitors, which have proven to have anti-cancer activity. Mechanism of ActionPARP...
