Filipin complex comprises a family of pentaene macrocyclic lactones first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Filipin complex consists of four...
Cerulenin is an epoxy fatty acid amide isolated from the fungus Cephalosporium caerulens identified as an antifungal in the 1960s. Over the past 40 years, cerulenin has found broad application in...
Filipin II is a minor component of the filipin complex, a family of pentaene antifungal metabolites first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955...
Filipin III is the major component of the filipin complex, a family of pentaene antifungal metabolites first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955...
Neoaureothin is an unusual chain-extended analogue of aureothin. Neoaureothin was first reported as a co-metabolite of neoantimycin in Streptomyces orinoci. Neoaureothin has anti-HIV and antifungal...
Antimycin A1 is the most hydrophobic of the four analogs of the Antimycin A complex. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of...
Tubercidin is a nucleoside metabolite first isolated from Streptomyces tubericidus. Tubercidin, like other nucleosides, is a broad spectrum potent chemotherapeutic agent active against viruses,...
Antimycin A2 is a homologue of the antimycin complex, first resolved from antimycin A1 in 1959. Antimycin A2, like all antimycins, is a potent inhibitor of respiration by inhibiting the oxidation of...
Antimycin A3 is an homolog of the Antimycin complex (syn: Antimycin A). Antimycin A3 is one of four closely related structures in the mixture (others include Antimycin A1, A2 and A4). First...
Antimycin A4 is the most polar of the major components of the antimycin complex, first isolated in 1958 from Streptomyces blastimyceticus and co-produced with antimycin A3. Antimycin A4 exhibits...
Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. Cochlioquinone A is anti-angiogenic and exhibits inhibitory activity against diacylglycerol...
Antimycin (syn: Antimycin A) is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces, first reported in the early 1950s for potent...
